Leslie Meserve

Physician · Internal medicine

15+ years of experience

Menopause Society Certified Practitioner

About Framework Health

Dr. Meserve is an internist who started Framework Health and has practiced in Newport Beach since 2004. It is a small concierge practice, and menopause care is part of the general membership rather than a separate program. She treats the effects of estrogen loss in women and low testosterone in men, and she frames her work around healthy aging, with sleep, heart risk and memory alongside hormones. Hormone therapy is used where it fits and alternatives where it does not. New patients start with a free 15 minute phone call. She sees patients in the Fashion Island office or by video, and her longtime office manager has worked with her since 2008.

Care

Treats

  • Perimenopause
  • Menopause
  • Hot flashes
  • Sleep problems
  • Mood & anxiety
  • Brain fog
  • Vaginal dryness
  • Low libido
  • Irregular periods

Prescribes

  • Hormone therapy
  • Testosterone
  • Weight medication
  • Lab testing

Particular focus

  • Bone health
  • Heart health
  • Thyroid
  • Weight & metabolism

Cost and insurance

Care is by membership, and visits aren’t billed to insurance.

Insurance

Doesn’t accept insurance

Ask whether they provide receipts for out-of-network reimbursement.

Self-pay

Available — prices aren’t published, ask for rates

Insurance can still be used for imaging, blood tests and other services outside the practice.

Verified October 2026.

Qualifications

MD, MSCP